Proinflammatory Actions of Thromboxane
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منابع مشابه
Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice.
Acute renal allograft rejection is associated with alterations in renal arachidonic acid metabolism, including enhanced synthesis of leukotrienes (LTs). LTs, the products of the 5-lipoxygenase (5-LO) pathway, are potent lipid mediators with a broad range of biologic activities. Previous studies, using pharmacological agents to inhibit LT synthesis or activity, have implicated these eicosanoids ...
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